In a nutshell – maps on computers
More specifically – A geographic information system (GIS) integrates hardware, software, and data for capturing, managing, analyzing, and displaying all forms of geographically referenced information.
GIS allows us to view, understand, question, interpret, and visualize data in many ways that reveal relationships, patterns, and trends in the form of maps, globes, reports, and charts.
A GIS helps you answer questions and solve problems by looking at your data in a way that is quickly understood and easily shared.